Human Diagnostics
- Blood & Cell
- Universal Pathogen
- Total RNA – Cell
- Total RNA – Blood
- PCR Cleanup
- Quick Plasmid
- Viral RNA
Blood and Cell DNA Extraction
Higher gDNA Yield and Purity
Quick 20 min Protocol
Effortless Magnetic Extractions
Single-Step Lysis and Capture of DNA
The magnetiQ Blood & Cell DNA Extraction Kit enables a rapid and efficient method of nucleic acid isolation from whole blood samples, ie. DNA extraction from blood and cells, as well as cell suspensions. DNA extraction from blood and cells is achieved through single-step magnetic bead-based lysis and capture of DNA from cells in blood, tissue, or cell culture samples.
Achieve highly efficient capture/elution of nucleic acids yielding purified solutions with minimal protein and salt contamination for downstream applications such as PCR and sequencing. Obtain purified and high concentrations of gDNA free of cell debris, salt, lipid and protein contamination in under 15 minutes.
More Info
- High DNA recovery and quality of varying sizes
- DNA extraction from white blood cells
- Short and scalable protocol
- Cost effective extractions
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open liquid handling systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated protocols.
Available in prefilled plate formats for automated extraction of Blood and Cell DNA.
- Performance
- Specifications
- Documentation
The magnetiQ Blood & Cell DNA Extraction Kit alleviates the need for separate lysis and binding, heating, or centrifugation steps. The purified sample can be concentrated in volumes as low as 25 μL, in contrast to column-based kits which often necessitate larger elution volumes. The magnetiQ Blood & Cell DNA Extraction Kit displays superior performance in comparison to leading commercially available column-based kits. A high quantity of DNA is extracted from cell suspension using the magnetiQ Blood & Cell DNA Extraction Kit, resulting in a lower CT value for GAPDH gene.
The magnetiQ Blood & Cell DNA Extraction Kit also provides cleaner, less contaminated eluted nucleic acid preparations from 100 μL whole blood or cell suspension samples. The kit produces very pure and high-yield nucleic acid elute (ratio between 1.8-2.2) with high reproducibility.
-Extraction yield of gDNA from 100 uL of whole blood using Galenvs magnetiQ Blood/Cell kit and Qiagen DNeasy Blood & Tissue kit. Quantification of gDNA performed using Qubit BR DNA fluorescent assay measurement (n=3)-
-Gel electrophoresis of extracted gDNA from 100 uL whole blood samples (4x) comparing Galenvs and Qiagen kits. Galenvs isolated gDNA is higher molecular weight while Qiagen extraction shows DNA smears below gDNA bands-
Download magnetiQ Blood & Cell Extraction Kit Technical Specifications
Applications
- Next Generation Sequencing (NGS)
- PCR and qPCR gene amplification
- DNA methylation studies
- Copy number variation (CNV) studies
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging
- Eliminates organic solvent hazardous waste
- Requires only the use of a magnetic rack and standard pipettes
Blood & Cell DNA Extraction
The magnetiQ Blood & Cell DNA Extraction Kit contains optimized buffers for blood or cell lysis and DNA binding, washing and elution developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
DNA recovered
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Blood, Cells, Cell culture
Manual: 100 or 250 assays
Prefilled plates: 16 or 96 assays
100 µL
>98%
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) Lysis/Binding Buffer
(ii) Wash Buffer #1
(iii) Wash Buffer #2
(iv) Elution Buffer
(v) Proteinase K
Room temperature
Kit Size
100 preps
250 preps
16 preps ready-to-use prefilled plates
Product Code
BC0100
BC0250
BC0016
Universal Pathogen DNA / RNA Extraction Kit
Higher DNA/RNA From Any Pathogen/Sample Matrix
Fast 20 min Protocol
One-Step Magnetic Extractions and Purification
Automatable /High Throughput
The magnetiQ Pathogen Extraction Kit is designed to simplify the extraction of pathogenic DNA and RNA from a variety of sample types. Using buffers and magnetic beads that were optimized to capture DNA and RNA, users can obtain a purified product in 15 minutes.
One-step magnetic bead-based extraction and purification of pathogenic DNA and RNA under 15 minutes from:
- Swab solutions (viral transport medium – VTM, and inactivation transport medium – ITM)
- Serum/plasma
- Blood and Exudate
- Saliva samples
- Cell-free body fluids
- Complex matrices such as sputum or stool
- Cerebrospinal fluid (CSF)
The Pathogen Extraction Kit provides a safe, simple and reproducible method for obtaining purified nucleic acid products. These can be used for downstream applications such as PCR, RT-PCR and Next Generation Sequencing (NGS).
More Info
- Pathogen purification for high DNA & RNA recovery and quality of varying sizes
- Short and scalable protocol
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated platforms.
No carrier RNA or Proteinase K required.
Available in prefilled plate formats for automated extraction of Pathogen DNA and RNA.
- Performance
- Specifications
- Documentation
Universal Pathogen DNA / RNA Extraction Kit
The magnetiQ Pathogen Extraction kit enables researchers to obtain a pure, contaminant free product. Its chemistry is optimized to lyse cells and wash away protein, lipid, salt and any other contaminants to yield a high purity sample. Our lysis buffer disrupts the components of the matrix enabling our magnetic beads to specifically target nucleic acids, which are subsequently purified from contaminants by the washing buffers and eluted in the final step of the process. The Pathogen Extraction kit has been optimized for 200 µl of sample from which the DNA or RNA is eluted in 50-100 µl, however there is some flexibility in the protocol. Researchers have the capacity to use a range of sample from 100-400 µl and to increase the concentration of the product by eluting in volumes as low as 50 µl. DNA and RNA can be recovered from initial concentrations as low as 1 copy/µl.
The magnetic beads used in the lysis buffer were developed to bind to DNA as well as RNA of different sizes with high specificity, without the use of Carrier RNA. This eliminates the need for any centrifugation step, filters, requires a minimal amount of collection tubes and can be easily applied to high throughput applications. It does not require any additives such as proteinase K or RNA carrier.
Galenvs vs Omega Universal Pathogen extraction kit
Galenvs vs Qiagen Universal Pathogen extraction kit
Download Full Comparison with Industry-Leading Kits from Omega & Qiagen
Applications
- Extraction of COVID-19 in clinical laboratories for the isolation and recovery of SARS-CoV-2 RNA
- Research and detection of viral and bacterial infection
- Quantification via Reverse Transcriptase qPCR (RT-qPCR)
- Next Generation Sequencing (NGS)
- Genomic DNA library preparation
- Copy number variation (CNV) studies
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging
- Eliminates need for Proteinase K treatment of swab samples
- Eliminates need for Carrier RNA in all sample types
- Eliminates centrifugation steps associated with spin-column based viral extraction kits
Universal Pathogen DNA / RNA Extraction Kit
The magnetiQ Pathogen Extraction Kit has buffers optimized for pathogenic RNA and DNA capture. The functionalized magnetic beads in the lysis buffer were developed to target and bind nucleic acids specifically. All the components are stored at room temperature.
Sample Type
Formats
Elution Volume
DNA recovered
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Swab, Saliva, Serum / Plasma, Blood, Stool, Urine, and Various transport media such as Universal Viral Transport medium (VTM), Inactive Transport Medium (ITM), Exudate, CSF
Manual: 50 or 200 assays
Automated: 16 assays
50-100 µL
>99%
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) Pathogen Lysis/Binding Buffer
(ii) Binding Magnetic Nanoparticles
(iii) Wash Buffer #1
(iv) Wash Buffer #2
(v) Elution Buffer
Room temperature
Kit Size
50 preps
200 preps
16 preps ready-to-use prefilled plates
96 preps ready-to-use prefilled plates
Product Code
UP0050
UP0200
UP0016
UP0096
[Manual] Quick Start Guide: Universal Pathogen Extraction Kit (UP0050 and UP0200)
[Manual] Quick Start Guide: Universal Pathogen Complex Module (UPX0100)
[Automated 16 samples] Quick Start Guide: Universal Pathogen Extraction Kit (UP0016)
[Automated 96 samples] Quick Start Guide: Universal Pathogen Extraction Kit (UP0096)
Technical Specifications and Comparison with Omega & Qiagen – Universal Pathogen Kit
Total RNA (Cell) Extraction
Higher DNA Yield/Purity
Fast 20 min Protocol
Effortless Magnetic Extractions
Automatable /High Throughput
The magnetiQ Total RNA (Cell) Extraction Kit enables a rapid and efficient method of extraction and purification of RNA and mRNA. DNA-free purification of RNA is achieved through magnetic bead-based capture and subsequent elution into a clean buffer. The kit alleviates the need for centrifugation steps and separate collection tubes – in contrast to standard column-based kits.
More Info
- High RNA recovery and quality of varying sizes
- Short and scalable protocol
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated platforms.
No carrier RNA or Protenaise K required.
Available in prefilled plate formats for automated extraction of Pathogen DNA and RNA.
- Performance
- Specifications
- Documentation
Total RNA (Cell) Extraction
The magnetiQ Total RNA Extraction Kit offers high yield and purity of RNA and mRNA. The purified sample can be concentrated in volumes as low as 50 μL, compared to column-based kits which often necessitate larger elution volumes. The magnetiQ Total RNA Extraction Kit performance demonstrates high purification efficacy at various fragment sizes. Sample processing is completed in less than 30 minutes, yielding high purity and efficient recovery of RNA and mRNA.
Download the Full Technical Specifications
Applications
- Next Generation Sequencing (NGS)
- Real-time RT-PCR
- Microarray
- Transcriptome profiling and analysis
- Poly-A purification
- Northern Blot
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging
- Eliminates organic solvent hazardous waste
Total RNA (Cell) Extraction
Contains optimized buffers for RNA binding, washing and elution developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Cells, cell culture
Manual: 100 or 250 reps
Preffilled Plates: 16 reps
50 µL or above
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) Binding Buffer
(ii) Binding Magnetic Particles
(iii) Wash Buffer 1
(iv) Wash Buffer 2
(v)Elution Buffer
Room temperature
Kit Size
100 preps
250 preps
16 preps ready-to-use prefilled plates
Product Code
TRC0100
TRC0250
TRC0016
Total RNA (Blood) Extraction
Higher RNA Yield/Purity
Fast 40 min Protocol
Effortless Magnetic Extractions
Automatable /High Throughput
The magnetiQ Total RNA (Blood) Extraction Kit enables a rapid and efficient method of extraction and purification of RNA and mRNA from blood samples. DNA-free purification of RNA is achieved through magnetic bead-based capture and subsequent elution into a clean buffer.
More Info
- High RNA recovery and quality of varying sizes
- Short and scalable protocol
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated platforms.
Available in prefilled plate formats for automated extraction of Pathogen DNA and RNA.
- Performance
- Specifications
- Documentation
Total RNA (Blood) Extraction
The magnetiQ Total RNA Blood Extraction Kit offers high yield and purity of RNA and mRNA. The purified sample can be concentrated in volumes as low as 50 μL, compared to column-based kits, which often necessitate larger elution volumes. The magnetiQ Total RNA Blood Extraction Kit performance demonstrates high purification efficacy at various fragment sizes. Sample processing is completed quickly, yielding high purity and efficient recovery of RNA and mRNA.
Download the Full Technical Specifications
Applications
- Next Generation Sequencing (NGS)
- Real-time RT-PCR
- Microarray
- Transcriptome profiling and analysis
- Poly-A purification
- Northern Blot
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging
- Eliminates organic solvent hazardous waste
Total RNA (Blood) Extraction
Contains optimized buffers for RNA binding, washing and elution developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Preserved blood
Manual: 100 , 250 Preps
Preffilled Plates: 16 Preps
50 µL or above
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
Part A: RNA Extraction
(i) Suspension Buffer
(ii) Binding Buffer
(iii) Proteinase K
(iv) Wash Buffer A1
(v) Wash Buffer A2
(vi) Elution Buffer A
(vii) Binding Beads A
Part B: DNase Treatment
(viii) DNase Reaction Buffer
(ix) Binding Beads B
(x) Binding Buffer B
(xi) Wash Buffer B1
(xii) Elution Buffer B
Room temperature
Kit Size
100 preps
250 preps
16 preps ready-to-use prefilled plates
Product Code
TRB0100
TRB0250
TRB0016
PCR Clean Up Kit
Low Elution Volumes
Quick 10 min Protocol
Effortless Magnetic Purification
Up to 99% of DNA Recovery
The magnetiQ PCR Clean Up Kit enables a rapid and efficient method of nucleic acid purification following enzymatic reactions such as PCR or other processes such as restriction digests or ligation reactions. Purification of DNA is achieved through magnetic bead-based capture and subsequent elution into clean buffer.
Obtain high DNA yield free of salt and protein contamination. Eliminate the need for spin columns and centrifugation with magnetic-based DNA capture and purification. Samples are processed manually in under 10 mins, requiring only the use of a magnetic rack and standard pipettes.
More Info
- PCR purification for high DNA recovery and quality of varying sizes
- Short and scalable protocol
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated platforms.
- Performance
- Specifications
- Documentation
- Video Protocol
PCR Clean Up
The magnetiQ PCR Clean Up Kit alleviates the need for centrifugation steps and separate collection tubes – in contrast to standard column-based kits. The magnetiQ PCR Clean Up kit capture efficiency is >98% of DNA in the size range of 100 bps – 10 kbps. The purified sample can be concentrated in volumes as low as 10 μL, compared to column-based kits which often necessitate larger elution volumes. The magnetiQ PCR Clean Up kit performance demonstrates high PCR purification efficacy at various fragment sizes. Sample processing is completed in less than 10 minutes, yielding high purity and efficient recovery of DNA.
Download Full Comparison
Promega/Roche/Galenvs PCR Cleanup Kits
Applications
- Next Generation Sequencing (NGS)
- Post-PCR and qPCR gene amplification
- Genomic DNA library preparation
- Copy number variation (CNV) studies
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging
- Eliminates organic solvent hazardous waste
PCR Clean Up
Contains optimized buffers for DNA binding, washing and elution developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
DNA recovered
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Enzymatic reactions (eg. PCR)
Manual: 100, 200, 250 preps
Prefilled plates: 16 preps
10 µL or above
>98%
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) Binding Buffer
(ii) Wash Buffer
(iii) Elution Buffer
Room temperature
Kit Size
100 preps
250 preps
16 preps ready-to-use prefilled plates
96 preps ready-to-use prefilled plates
Product Code
PC0100
PC0250
PC0016
PC0096
Quick Plasmid Miniprep
High Plasmid Purity and Recovery
Quick 15 min Protocol
Effortless Magnetic Extraction
High Transfection Efficiency
The magnetiQ Quick Plasmid Miniprep Kit enables a rapid and efficient method of plasmid extraction and purification without need for RNase supplement. The plasmid isolation kit provides extraction of plasmid supercoiled DNA through single-step magnetic bead-based lysis and capture of plasmids from transformed bacteria.
The magnetiQ Quick Plasmid Isolation Kit enables simple and rapid plasmid extraction from cultured bacteria in 15-20 minutes using magnetic nanoparticles. No need for spin columns and multiple centrifugation steps. Isolate highly pure concentrations of plasmid DNA with negligible gDNA, protein or endotoxin carryover.
More Info
- Plasmid isolation kit for high plasmid recovery without RNase
- Short and scalable protocol for both low and high-copy vectors
- Cost effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated protocols.
- Performance
- Specifications
- Documentation
Plasmid Miniprep
The magnetiQ Quick Plasmid Isolation Kit alleviates the need for centrifugation steps and separate collection tubes – in contrast to standard column-based kits. magnetiQ Quick Plasmid Miniprep Kit allows for facile bacterial lysis, bacterial plasmid binding, and endotoxin removal only using a standard magnetic rack. The purified bacterial plasmid DNA can be concentrated in volumes as low as 25 μL, compared to column-based kits which often necessitate larger elution volumes. The magnetiQ Quick Plasmid Miniprep Kit performance demonstrates high yield and pure plasmid DNA extraction for both low and high copy vectors. Sample processing is completed in less than 20 minutes, yielding high purity and efficient recovery of molecular biology grade plasmids.
Applications
• Molecular biology
• In Vitro transfection
• PCR, DNA sequencing, cloning
Features
• Amenable to high-throughput methods, including automation
• Faster and simpler magnetic collection and resuspension steps
• Reduces concern for clogging
• Eliminates RNase treatment
• Eliminates centrifugation steps with bacterial lysis and removal of cell debris, proteins, and denatured gDNA
Plasmid Miniprep
The magnetiQ Quick Plasmid Isolation Kit contains optimized buffers for molecular biology applications developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
DNA recovered
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Bacterial cell culture
Manual: 100, or 200 assays
Automatd: 16 or 96 assays
100 µL
>98%
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) GPL-1,
(ii) GPL-2,
(iii) Lysis/binding buffer,
(iv) Binding Magnetic Nanoparticles,
(v) Wash Buffer #1,
(vi) Wash Buffer #2,
(vii) Elution buffer(i) Binding Buffer
(ii) Wash Buffer
(iii) Elution Buffer
Room temperature
[Manual] Quick Start Guide: Quick Plasmid Miniprep Kit (QPM0100)
[Manual] Quick Start Guide: Quick Plasmid Miniprep Kit (QPM0200)
[Semi-Automated 16 samples] Quick Start Guide: Quick Plasmid Miniprep Kit (QPM0016)
[Automated 96 samples] Quick Start Guide: Quick Plasmid Miniprep Kit (QPM0096)
Viral RNA Extraction
IVD Approval – Health Canada
Fast 15 min Protocol
One-Step Magnetic RNA Extraction and Purification
Automatable/High Throughput
The magnetiQ Viral RNA Extraction Kit enables a rapid and efficient method of extraction and purification of viral RNA. Purification of viral RNA is achieved through magnetic bead-based capture and subsequent elution into clean buffer.
One-step magnetic bead-based extraction and purification of viral RNA under 15 minutes from:
- Swab solutions (viral transport medium – VTM, and inactivation transport medium – ITM)
- Saliva samples
- Cell-free body fluids
- Bronchoalveolar lavage fluid
The magnetiQ Viral RNA Extraction Kit purification procedure is designed to ensure safe and reproducible handling of potentially infectious samples. Obtain purified and high concentrations of RNA free of debris, salt, lipid and protein contamination.
More Info
- High viral RNA recovery and quality of varying sizes
- Short and scalable protocol
- Rapid and cost-effective extractions
- Non-toxic chemicals
- Automatable on open systems
Available in a range of formats designed to meet different sample size and throughput needs and designed for both manual and fully automated protocols.
- Performance
- Specifications
- Documentation
Viral RNA Extraction
The magnetiQ Viral RNA Extraction Kit alleviates the need for centrifugation steps and separate collection tubes – in contrast to standard column-based kits. The magnetiQ Viral RNA Extraction capture efficiency is >99% of viral RNA. The purified sample can be concentrated in volumes as low as 25 μL, compared to column-based kits which often necessitate larger elution volumes. The magnetiQ Viral RNA Extraction Kit performance demonstrates high purification efficacy at various fragment sizes. Sample processing is completed in less than 15 minutes, yielding high purity and efficient recovery of viral RNA.
Viral RNA Extraction Galenvs vs Norgen vs Zymo
See Full Comparison – Galenvs/Norgen/Zymo Viral RNA Extraction Kits
Applications
•
- Diagnostics (IVDD) of COVID-19 in clinical laboratories for the isolation and recovery of SARS-CoV-2 RNA from patient samples
- Quantification via Reverse Transcriptase qPCR (RT-qPCR).
- Next Generation Sequencing (NGS)
- Genomic DNA library preparation
- Copy number variation (CNV) studies
Features
- Amenable to high-throughput methods, including automation
- Faster and simpler magnetic collection and resuspension steps
- Reduces concern for clogging.
- Eliminates need for proteinase K treatment of swab samples
- Eliminates centrifugation steps associated with spin-column based viral extraction kits
Viral RNA Extraction
The magnetiQ Viral RNA Extraction Kit contains optimized buffers for viral RNA capture and purification developed with Galenvs’ functionalised magnetic beads and optimized with machine-learning approaches for protocol development and reagent formulation.
Sample Type
Formats
Elution Volume
DNA recovered
Processing Mode
Throughput
Binding Technology
Binding Capacity
Components
Storage
Swab, Saliva, Various transport media such as Universal Viral Transport medium (VTM), Inactive Transport Medium (ITM), and swab preservative fluid, cell-free body fluids, , culture supernatants, bronchoalveolar lavage fluid
Manual: 20, 200,250 assays
Prefilled plates: 16 or 96 assays
25 µL or above
>99%
Automated; Manual. Compatible with 96-well plates.
1-250 samples per run
Magnetic beads
Scalable
(i) Viral Lysis/Binding Buffer
(ii) Wash Buffer #1
(iii) Wash Buffer #2
(iv) Elution Buffer
Room temperature
Kit Size
100 preps
250 preps
16 preps ready-to-use prefilled plates
96 preps ready-to-use prefilled plates
Product Code
VR0100
VR0250
VR0016
VR0096
[Manual] Quick Start Guide: Viral RNA Extraction Kit (VR0100 and VR0250)
[Automated 16 samples] Quick Start Guide: Viral RNA Extraction Kit (VR0016)
[Automated 96 samples] Quick Start Guide: Viral RNA Extraction Kit (VR0096)
Viral RNA Extraction Kit Handbook
Tech Spec Sheet — Viral RNA Extraction—COVID-19
IVDD Validation — Viral RNA Extraction Kit— SARS-CoV-2